The Pten and Tsc1 genes both Ski de fond - Skis a roulettes encode proteins that repress mechanistic target of rapamycin (mTOR) signaling.Disruption of either gene in the brain results in epilepsy and autism-like symptoms in humans and mouse models, therefore it is important to understand the molecular and physiological events that lead from gene d
Lessons learned after one year of COVID-19 from a urologist and radiotherapist view: A German survey on prostate cancer diagnosis and treatment
Introduction Since the beginning of the pandemic in 2020, COVID-19 has changed the medical landscape.International recommendations for localized prostate cancer (PCa) include deferred treatment and adjusted therapeutic routines.Materials and methods To longitudinally evaluate changes in PCa treatment strategies in urological and radiotherapy depart
RNase R, a New Virulence Determinant of Streptococcus pneumoniae
Pneumococcal infections have increasingly high mortality rates despite the availability of vaccines and antibiotics.Therefore, the identification of new virulence determinants and the understanding of the molecular mechanisms behind pathogenesis have become of paramount importance in the search of new targets for drug Detox Products development.The
Data-driven prediction of plate velocities and plate deformation of explosive reactive armor
Explosive reactive armor (ERA) is currently being actively developed as a protective system for mobile devices against ballistic threats such as kinetic energy penetrators and shaped-charge jets.Considering mobility, the aim is to design a protection system with a minimal amount of required mass.The efficiency of an ERA is sensitive to the impact p
Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk
Abstract In mice, periodic cycles of a fasting mimicking diet (FMD) protect normal cells while killing damaged STRUCTURE MASK cells including cancer and autoimmune cells, reduce inflammation, promote multi-system regeneration, and extend longevity.Here, we performed secondary and exploratory analysis of blood samples from a randomized clinical tria